Comment by 🚀 stack
Re: "Hello. Welcome to the chemicals of your brain. Today:…"
Also how do I get my hands on some glutamate? I think I am having said 'cognitive problems' What form is it in?
2025-01-14 · 1 year ago
13 Later Comments ↓
🍀 gritty · 2025-01-14 at 22:01:
is this included in supplements?
insert
Y'all got any more of them glutamates?
meme here :)
👻 darkghost · 2025-01-15 at 00:20:
Glutamate is the anionic form of glutamic acid, one of the non-essential amino acids. Before you start sprinkling monosodium glutamate all over everything you eat, it does not freely cross the blood brain barrier so you cannot supplement your neurotransmitter levels through diet.
🐰 AsherFisc [OP/mod] · 2025-01-15 at 02:51:
As @darkghost mentioned. It is not possible to supplement it, but you can modulate it with certain drugs - mainly nootropics.
🚀 stack · 2025-01-15 at 02:53:
I have an idea: can we inject it directly into the brain? like into the neck?
🐰 AsherFisc [OP/mod] · 2025-01-15 at 02:56:
I wouldn’t recommend that @stack. It might be too dangerous!
Also, there are so many other neurotransmitters that are involved in cognition: dopamine, serotonin, acetylcholine, histamine (yes, the allergy one), norepinephrine, GABA, among all the others.
🚀 stack · 2025-01-15 at 03:03:
So many things to inject into the neckhole!
🚀 stack · 2025-01-15 at 03:10:
Sorry, I don't mean to be disruptive. I appreciate your effort to provide this information I wouldn't otherwise come across.
🐰 AsherFisc [OP/mod] · 2025-01-15 at 15:32:
No! This is meant for fun, anyway! Inject it into your neckhole...see what happens >:)
👻 darkghost · 2025-01-15 at 16:20:
Injection of sloppily compounded pharmaceuticals into the cerebrospinal fluid is what killed a number of people a few years back. I think it was NECC.
🐰 AsherFisc [OP/mod] · 2025-01-15 at 16:57:
Oh, I bet! It's definitely not something to mess around with! treat your nervous system with respect. RESPECT!!!
🚀 stack · 2025-01-15 at 17:01:
Or at least keep your lab clean if you are injecting substances into your brain...
🐦 wasolili [...] · 2025-01-15 at 22:37:
Serotonin doesn't cross the blood brain barrier either, so some people take 5-htp, a serotonin precursor which crosses the blood brain barrier and is then¹ converted to serotonin. Is there anything similar to glutamate?
Be careful when messing with glutamate.
Are there any reasons, good or bad, why people mess with glutamate outside of a medical setting?
¹ although to be pedantic, "then" is a bit inaccurate. while 5-htp does convert to 5-ht while in the brain, it also converts to 5-ht elsewhere as well, leading to lots of the 5-htp metabolizing into 5-ht elsewhere in the body and thus never reaching the brain. (at least, this is my layperson understanding of the process, correct me if I'm wrong)
Original Post
Hello. Welcome to the chemicals of your brain. Today: glutamate. Glutamate is the primary excitatory neurotransmitter in your brain. It basically is the “gas petal” of the brain. Too much makes your cells work themselves to death and causes cognitive problems, and too little also leads to cognitive problems. Too much can also cause seizures. Be careful when messing with glutamate. I will now take questions. Please ask your questions! edit: 'gas pedal' - not 'petal' I did legitimately struggle...